JAMA Network Announces New Journal, JAMA AI, to Launch in Early 2027

The online-only title, edited by Roy Perlis, will pair AI-driven assessment with human peer review and cover apps, wearables and imaging as well as AI.

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330 North Wabash in Chicago, also known as AMA Plaza, where the American Medical Association has offices. Weekly-Document8334, CC BY 4.0, via Wikimedia Commons · CC BY 4.0

Key points

  • JAMA AI will be the JAMA Network's 14th journal and will launch and open to submissions in early 2027.
  • Every research article will get an AI-driven assessment alongside human peer review; human editors make final decisions.
  • The editors say AI-related submissions to JAMA Network journals have more than doubled since 2023.

The JAMA Network will launch a new journal devoted to artificial intelligence in medicine, JAMA AI, in early 2027, its editors announced on Thursday in an editorial published in JAMA. It will be the network's 14th journal.

The editorial, by Roy H. Perlis, Annette Flanagin and Kirsten Bibbins-Domingo, names Perlis as the inaugural editor. The journal will begin accepting submissions when it launches.

"JAMA AI will be a fully online journal and will publish content as soon as it is accepted, edited, and produced," the editors wrote. The editorial does not state whether the journal will be open access.

Scope and peer review

According to the editorial, the journal will cover AI in health care from foundational advances to real-world clinical implications. Its scope also includes other computational tools and technologies, among them mobile apps, wearable sensors, digital imaging and pathology, and virtual reality. Studies of technology's broader effects on health, including AI and social media, are also in scope. The editors said work must be rooted in medicine, with the aim of improving human health, and that clinical care is a stated focus.

Each research article will receive an AI-driven assessment and review in addition to standard human peer review, and the editors said the AI tools will also be used to support human reviewers. They wrote that "human editors will remain the decision-makers for all of the manuscripts we consider."

The editors wrote that authors and reviewers must "fully disclose and assume responsibility for any AI use," and that "transparency in all aspects of the process" is a core principle. The editorial does not say how the AI review tools were developed or tested.

What it will publish

Alongside clinical research using "the full range of computational tools," the editors said the journal will run Invited Commentaries accompanying many articles and Viewpoints, and plans multimedia and social media amplification of its content.

Why the network says it needs a new journal

The editorial cites growth in the AI literature: PubMed indexed 1,249 AI articles in 2000, 22,791 in 2020 and 80,042 in 2025, according to the editors. They wrote that AI-related manuscripts submitted to JAMA and the JAMA Network journals have more than doubled since 2023 and now exceed what those journals can publish, and they presented JAMA AI as an additional venue to meet that demand.

The network already runs an AI channel, JAMA+ AI, which collects AI research and commentary from across its journals. The channel page lists a podcast episode, "JAMA AI: A New JAMA Network Journal," dated October 15, 2026, alongside the editorial.

The editorial places AI tools inside the review of every research paper submitted to the new title, with final decisions kept with human editors. It does not describe the specific systems that will be used.

The editorial does not name an editorial board or describe article processing charges.

Sources

  1. Announcing JAMA AI—A New Journal From the JAMA Network, JAMA, October 15, 2026
  2. JAMA+ AI channel, JAMA Network, October 15, 2026